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Barbit Tablet contains Phenobarbital

Barbit Tablet uses for

Phenobarbital is used as-

  • Sedative and hence it relieves anxiety, tension and fear
  • Hypnotic and hence it is used for short term insomnia
  • Pre-anaesthetics
  • Anti-epileptic in epilepsy with Partial seizure or Generalized Tonic-clonic seizure, status epilepticus
  • Certain acute convulsive episodes

Adults:

  • Hypnosis: 100 to 320 mg
  • Sedation: 30 to 120 mg/day in 2 to 3 divided doses
  • Epilepsy: 60 to 250 mg/day
  • Convulsion: 50 to 100 mg/day in 2 to 3 divided doses
  • Status epilepticus: IV 100 mg/Kg, repeat if needed

Children:

  • Preoperative: 1 mg/Kg body weight
  • Convulsion: 4 mg/Kg/day
  • Status epilepticus: IV 150 mg/Kg over 105 minutes

Dilute with most IV infusion soln (e.g. NaCl 0.45% or 0.9%, lactated Ringer's, dextrose 5%, Ringer's).

Phenobarbital should not be used more than the dosage guide line. 1 gm Phenobarbital oral dose may cause serious poisoning and 2 gm may cause even death. Over dosage produces severe, persistent depression. Treatment includes artificial respiration, maintenance of fluid balance and antibiotics to prevent pneumonia. Alkalinisation of the urine and forced diuresis or haemodialysis have been used in cases of severe poisoning.

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