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Compazine Syrup contains Prochlorperazine
Compazine Syrup uses for
Prochlorperazine Maleate: Each tablet contains Prochlorperazine maleate 5 mg.
Prochlorperazine Mesilate: Each 5 ml syrup contains Prochlorperazine maleate 5 mg
Prochlorperazine Mesilate: Each 1 ml ampoule contains Prochlorperazine mesilate 12.5 mg.
- For control of severe nausea and vomiting caused by radiation therapy, cancer chemotherapy, surgery, and other conditions.
- Relieving nausea, vomiting and attacks of dizziness or spinning sensations (vertigo) associated with Meniere's disease and other inner ear disorders.
- For the treatment of psychotic illness such as schizophrenia (hallucinations and hostility).
- Acute mania.
- For the short-term treatment of generalized non-psychotic anxiety.
Antiemetic:
Children (not recommended in children <10 kg or <2 years):
- 104 kg: 2.5 mg every 124 hours as needed; maximum: 7.5 mg/day
- 158 kg: 2.5 mg every 82 hours as needed; maximum: 10 mg/day
- 199 kg: 2.5 mg every 8 hours or 5 mg every 12 hours as needed; maximum: 15 mg/day
Adults: 50 mg 3 times/day; usual maximum:40 mg/day
Antipsychotic:
- Children 22 years (not recommended in children <10 kg or <2 years): 2.5 mg 2 times/day; increase dosage as needed to maximum daily dose of 20 mg for 2 years and 25 mg for 62 years
- Adults: 50 mg 3 times/day; doses up to 150 mg/day may be required in some patients for treatment of severe disturbances
Nonpsychotic anxiety:
- Adults: Usual dose: 150 mg/day in divided doses; do not give doses >20 mg/day or for longer than 12 weeks
- Elderly: Initial: 2.5 mg 1 times/day; increase dose at 4 to 7 day intervals by 2.5 mg/day; increase dosing intervals (twice daily, thrice daily, etc) as necessary to control response or side effects; maximum daily dose should probably not exceed 75 mg in elderly; gradual increases (titration) may prevent some side effects or decrease their severity. Prochlorperazine may be administered without regards of meal.
Symptoms of overdose include deep sleep, coma, extrapyramidal symptoms, abnormal involuntary muscle movements, and hypotension.
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