1 Answers
Pulmoten Tablet contains Bosentan Monohydrate
Pulmoten Tablet uses for
Treatment of pulmonary arterial hypertension (PAH) to improve exercise capacity and symptoms in patients with WHO functional class III
Adult/Geriatric:
- <40 kg: Initial and maintenance: 62.5 mg twice daily
- ≥40 kg: Initial: 62.5 mg twice daily for 4 weeks; increase to maintenance dose of 125 mg twice daily. Doses more than 125 mg twice daily do not appear to confer additional clinical benefit but may increase risk of liver toxicity.
Pediatric:
- Infants ≥7 months and Children: Limited data available (Barst 2003; Ivy 2004; Maiya 2006; Rosenzweig 2005):
- 5 to <10 kg: Initial: 15.6 mg daily for 4 weeks; increase to maintenance dose of 15.6 mg twice daily.
- 10 to 20 kg: Initial: 31.25 mg daily for 4 weeks; increase to maintenance dose of 31.25 mg twice daily.
- >20 to 40 kg: Initial: 31.25 mg twice daily for 4 weeks; increase to maintenance dose of 62.5 mg twice daily.
- >40 kg: Initial: 62.5 mg twice daily for 4 weeks; increase to maintenance dose of 125 mg twice daily.
- Children >12 years and Adolescents: Refer to adult dosing.
Symptoms: Nausea, vomiting, hypotension, dizziness, sweating and blurred vision.
Management: Symptomatic and supportive treatment.
Read more here Pulmoten
1613 views
Answered