What does Carmapine CR Tablet (Controlled Release) used for?

Carmapine CR Tablet (Controlled Release) contains Carbamazepine

Carmapine CR Tablet (Controlled Release) uses for

Carbamazepine is indicated for-

• partial and secondary generalized tonic-clonic seizures
• Primary generalized tonic-clonic seizures
• Trigeminal neuralgia
• Prophylaxis of bipolar disorder

Epilepsy:

• Adult: Initially, 10000 mg once daily or bid, gradually increased by increments of up to 200 mg daily every wk. Maintenance: 0.8.2 gm daily in divided doses. Max: 2 gm daily.
• Child: 100 mg/kg daily in divided doses. Alternatively, <1 yr 10000 mg daily. Max: 35 mg/kg daily; 1 yr 20000 mg daily. Max: 35 mg/kg daily; >50 yr 40000 mg daily. Max: 1 gm daily; >105 yr 0.6 gm daily. Max: 1 gm daily.

Prophylaxis of bipolar disorder:

• Adult: Initially, 400 mg daily in divided doses, increased gradually as necessary. Maintenance: 40000 mg daily in divided doses. Max: 1.6 gm daily.

Trigeminal neuralgia:

• Adult: Initially, 10000 mg bid, increased gradually as needed. Maintenance: 40000 mg daily in divided doses. Max: 1.2 gm daily.

Symptoms: Dizziness, ataxia, drowsiness, stupor, nausea, vomiting, opisthotonos, restlessness, agitation, disorientation, tremor, involuntary movements, adiadochokinesis, abnormal reflexes (hypoactive or hyperactive), mydriasis, nystagmus, flushing, cyanosis, urinary retention. Hypotension or HTN may develop. Coma may follow.

Management: Induce emesis or employ gastric lavage. General supportive treatment.

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