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G-Salbutamol Solution for Inhalation contains Salbutamol (Respirator Solution)
G-Salbutamol Solution for Inhalation uses for
Salbutamol Respirator Solution is indicated for the treatment of severe acute asthma (status asthmaticus) and also forms of bronchospasm.
By Intermittent Administration:
Adult: salbutamol Respirator Solution 0.5.0 ml should be diluted to final volume of 2.0.0 ml with normal saline for injection. The resulting solution is inhaled from a suitably driven nebuliser until aerosol generation ceases. Using a correctly matched nebuliser and driving source this should take about 10 minutes.Salbutamol Respirator Solution may be used undiluted for intermittent administration. For this 2.0 ml of the solution is placed in the nebuliser and the patient allowed to inhale until bronchodilatation is achieved. This usually takes 3 minutes. Some adult patients may require higher doses of salbutamol upto 10 mg in which case nebulisation may continue until aerosol generation ceases.
Children under 12 years age: 0.5 ml of the solution diluted to 2 ml with normal saline. Some children may however require higher doses of upto 1 ml of the solution. Intermittent treatment may be repeated four times a day.
By Continuous Administration:
Salbutamol Respirator Solution is diluted with normal saline for injection, 1 ml solution made upto 100 ml with diluent. The diluted solution is administered as an aerosol by a suitably driven nebuliser. The usual rate of administration is 1 to 2 mg/hour. Delivery of the aerosol may be by face mask or via an endotracheal tube. Intermittent positive pressure may be used but is rarely necessary. When there is risk of anoxia through hypoventilation, oxygen should be added to the inspired air.
During continuous administration any signs of overdosage may be counteracted by withdrawal of the drug. The preferred antidote for overdosage is a cardioselective betablocker, but betablockers should be used with caution in patients with a history of bronchospasm.
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