Serum free hemoglobin test
What is a Serum Free Hemoglobin Test?
A serum free hemoglobin test is a diagnostic test conducted to determine the presence of high levels of free hemoglobin in the blood serum. It is commonly used to diagnose conditions such as anemia, kidney disease, congestive heart failure, and other diseases associated with the destruction of red blood cells. During this test a sample of blood is analyzed to determine the level of free hemoglobin present in the blood serum.
What is the Preparation for a Serum Free Hemoglobin Test?
No special preparation is generally required for a serum free hemoglobin test. However, the patient should inform their doctor of any medications or supplements they are taking as these may interfere with the test results. It is also recommended that the patient fast for 4 hours prior to the test.
How is a Serum Free Hemoglobin Test Performed?
The procedure involved in a serum free hemoglobin test is relatively simple. During the first step, a sample of blood is taken from the patient's arm. Next, the sample is sent to a laboratory where it is tested for the presence of free hemoglobin in the blood serum. The laboratory results are usually available within 1-2 days.
Types of Serum Free Hemoglobin Tests
There are two main types of serum free hemoglobin tests available:
- Immunoturbidimetric – this method uses antibodies and light to detect the presence of free hemoglobin in the serum sample. It is the most common and accurate technique for detecting free hemoglobin.
- Hemiglobincyanide – this method uses a reagent to bind to the free hemoglobin and produce a color reaction. The intensity of the color reaction indicates the level of free hemoglobin in the sample.
Risks of a Serum Free Hemoglobin Test
A serum free hemoglobin test is generally a safe and low risk procedure. The risks associated with this test include bruising and soreness of the arm from where the blood sample was taken and a small risk of infection if the needle is not sterile. Additionally, the patient may experience discomfort from the needle prick.
Why is a Serum Free Hemoglobin Test Performed?
A serum free hemoglobin test is performed to measure the level of free hemoglobin in the blood serum. This test is used to diagnose various conditions, which include:
- Anemia – low hemoglobin levels in the blood caused by lack of nutrients such as iron, folate, or vitamin B12.
- Kidney disease – high hemoglobin levels in the blood caused by the destruction of red blood cells due to kidney damage.
- Congestive heart failure – elevated levels of free hemoglobin in the blood caused by the destruction of red blood cells due to cardiac problems.
- Excessive alcohol consumption – high levels of hemoglobin in the blood caused by alcohol related damage to red blood cells.
When is a Serum Free Hemoglobin Test Performed?
A serum free hemoglobin test can be ordered by a doctor at any time to determine the level of free hemoglobin in the blood serum. A doctor may order this test if a patient is exhibiting the symptoms of anemia, kidney disease, or congestive heart failure. Additionally, this test may be requested to determine the level of free hemoglobin in the blood as part of a general health checkup.
