Liver function tests
What are Liver Function Tests?
Liver function tests (LFTs) are blood tests used to assess the health of your liver. It is used to detect, diagnose, evaluate, and monitor diseases of the liver. This test can measure the amount of enzymes such as aminotransferases and bilirubin in the blood as well as blood proteins, so it is a reliable indicator of your liver health.
Why Liver Function Tests?
Liver tests are used to check for any liver damage, infection or inflammation or any evidence of cirrhosis (scarring). These tests can also detect any underlying conditions or diseases, such as hepatitis, alcohol-related liver disease, or non-alcoholic fatty liver disease (NAFLD). The test helps to determine the prognosis of the liver disorder and the level of treatment required.
Preparation
For most liver tests, you don’t need special preparation. However, you should let your healthcare provider know if you are taking any vitamins, supplements or other medications. These tests usually require a simple blood sample.
Procedure
The procedure for most liver function tests includes:
- The healthcare provider will take a blood sample from a vein, typically from the inside of your elbow or the back of your hand.
- The sample is sent to a laboratory for testing.
- The laboratory will test the sample for the presence of certain enzymes and proteins.
- The results are then sent to your healthcare provider, who will review the results.
Types of Liver Function Tests
The different types of liver function tests include:
- Alanine aminotransferase (ALT): It measures the activity of the enzyme ALT, which is produced mostly by the liver.
- Aspartate aminotransferase (AST): It measures the activity of the enzyme AST, which is produced mostly by the liver.
- Alkaline phosphatase (ALP): It measures the amount of ALP enzyme produced by the liver.
- Bilirubin: It measures the amount of bilirubin, a yellow pigment that results from the breakdown of red blood cells.
- Gamma-glutamyl transferase (GGT): It measures the amount of GGT enzyme produced by the liver.
- Protein: it measures the amount of protein in the blood.
- Albumin: it measures the amount of albumin in the blood.
Risks of Liver Function Tests
Liver function tests are generally considered safe and pose minimal risks. There is a small chance of bruising or infection at the site of the needle insertion. Other risks associated with liver function tests include:
- Allergic reactions to the needle.
- Lightheadedness or dizziness.
- Fainting.
When should you have liver function tests?
Your doctor may recommend liver function tests if they suspect you may have a liver disease. They may also recommend this test if you are taking any medications or have any medical conditions that may affect your liver.
It is also important to have a regular liver function tests to monitor your liver health, particularly if you have a family history of liver disease or if you drink alcohol regularly.