17-Hydroxyprogesterone
What is 17-Hydroxyprogesterone?
17-Hydroxyprogesterone (17-OHP) is a hormone produced by the body, found most in women during pregnancy. It helps the development and maintenance of a pregnancy, as well as normal hormone balance. It also helps the placenta to make other hormones, such as estrogen and progesterone.
Preparation and Procedure for Test of 17-Hydroxyprogesterone
Your doctor may want you to have a test of 17-hydroxyprogesterone levels. You may be asked to do the following:
- Provide a blood sample.
- Ensure you have a lab form provided by your doctor.
- If you are pregnant, your doctor may advise you to get the test in the second or third trimester.
Types of 17-Hydroxyprogesterone Tests
The following are the different types of 17-hydroxyprogesterone tests your doctor may recommend:
- Baseline 17-hydroxyprogesterone test that is done to find out your baseline 17-hydroxyprogesterone level in the first trimester of your pregnancy.
- 17-hydroxyprogesterone test during pregnancy to monitor the development of 17-hydroxyprogesterone levels over time.
- 17-hydroxyprogesterone challenge test to check your reaction to a hormone that your body produces in response to a low dose of 17-hydroxyprogesterone.
Reasons to Test 17-Hydroxyprogesterone Levels
The testing of 17-hydroxyprogesterone levels is recommended in order to monitor the health of the fetus and the mother during pregnancy. The test can also indicate if there is an increased risk of certain medical conditions related to hormonal imbalances, such as congenital adrenal hyperplasia, which can cause birth abnormalities. Additionally, the test can help detect other medical conditions, such as ovarian cancer, and can help monitor individuals for steroid deficiency or production.
Risks of Test for 17-Hydroxyprogesterone Level
The risks associated with testing for 17-hydroxyprogesterone levels are minimal, but they include:
- Irregular Bleeding
- Blood Clots
- Infection
- Liver Damage
- Allergic Reaction
- Abnormal Result
When to Test for 17-Hydroxyprogesterone Level
Your doctor may recommend a test for 17-hydroxyprogesterone levels if the mother is pregnant. It is important to get the test done as soon as possible, because high levels of 17-hydroxyprogesterone can indicate a risk of certain medical conditions or birth abnormalities in the fetus. Additionally, if the mother has been having unusual menstrual cycles or has any symptoms related to hormonal imbalances, the doctor may also recommend testing for 17-hydroxyprogesterone levels.
