Stool Elastase
Stool Elastase: Overview
Stool Elastase (SE) is a digestive enzyme, produced by the pancreas, that helps to breakdown fat and proteins. It is measured in Stool Elastase units (SEU). SEU values are used to assess the activity and health of the pancreas and the digestive system. Low levels of SEU may indicate a decreased function of the pancreas and an illness such as chronic pancreatitis or pancreatic cancer. High levels of SEU may indicate an increase in the amount of fat and protein being broken down in the gut, or a health condition such as pancreatic hypersecretion. SE tests are generally done in combination with other tests to diagnose pancreatic diseases.
Stool Elastase: Preparations
Stool Elastase test requires no preparation. The patient will need to provide a fresh sample of their stool. The sample must be collected in a sterile, leak-proof container and taken to the laboratory as soon as possible.
Stool Elastase: Procedure
The SE test is done in a laboratory. In the lab, the sample is analyzed for SE levels. The results of the SE test are usually reported in SE units (SEUs). The normal range of SEUs is 40-200 SEU/g.
Stool Elastase: Types
There are three types of SE tests:
- Direct ELISA (enzyme-linked immunosorbent assay): This is a simple and easy to use test that measures the amount of SE in the stool sample.
- Immunofluorescence Assay (IFA): This is a more sensitive method of measuring SE levels in the stool sample.
- Radioimmunoassay (RIA): This is a more time-consuming and expensive method of measuring SE levels in the stool sample.
Stool Elastase: Risks
No risks are associated with the SE test. There are no risks to taking a sample of stool.
Stool Elastase: Why and When to Do it?
The SE test is done to measure the amount of enzyme produced by the pancreas and to help diagnose pancreatic diseases such as chronic pancreatitis or pancreatic cancer. The SE test should be done when one or more signs and symptoms of pancreatic diseases are present.
