Lung Cancer Genetic Tests

Lung Cancer Genetic Tests

Lung cancer genetic testing is one of the most important tests for detecting and preventing the progression of lung cancer in individuals with a higher risk of developing the disease. Genetic testing is a way to study important genes associated with a disease to find out if a person carries variants linked to the disease. A genetic test can help identify if someone is at a higher risk for certain types of cancer, such as lung cancer, and provide information about potential treatments and how to better monitor for cancer risk.

Preparation for the Test

Your healthcare provider may recommend genetic testing for lung cancer if you are at increased risk due to family history or other factors. While performing the test, your healthcare provider will ask about your family medical history (cancer, disease, etc.), lifestyle, and other risk factors. Be sure to provide accurate information, as it is important for determining if you are at risk of the disease.

Procedure of the Test

The procedure for performing a genetic test is quite simple and involves taking a small sample of cells from the body, typically from a swab in the oral cavity. Additionally, a blood sample may be taken to measure the levels of specific proteins or genetic markers in the body. A high level of these markers can indicate an increased risk of developing the disease.

Types of Genetic Tests

Genetic testing for lung cancer is divided into two main types:

• Targeted genetic tests: These tests can be used to detect mutations in specific genes that are linked to an increased risk of lung cancer. Common genes targeted in these tests are BRCA1, BRCA2, TP53, K-RAS, and EGFR.
• Multi-gene Panel Tests: These tests are used to detect several different mutations in multiple genes. The panel test is more comprehensive and can detect a wide range of mutations in many genes associated with an increased risk of developing lung cancer.

Risks of the Test

Genetic testing for lung cancer is generally safe and poses no risk of developing the disease. However, it is important to remember that not everyone who has a genetic variant linked to the disease will actually develop it.

Why is the Test Done?

Genetic testing is used to identify individuals at higher risk of developing lung cancer or those who may have a more aggressive form of the disease. The results of the test can help healthcare providers determine which treatments may be most effective and monitor people who are at an increased risk more closely.

When is the Test Done?

Genetic testing is typically recommended for individuals who are at higher risk of developing lung cancer, including those who have a family history of the disease, have been exposed to smoking or other carcinogens, or have been successfully treated for lung cancer in the past. Genetic testing can be performed at any age.