Beta 2 Microglobulin (B2M) Tumor Marker Test

What is a Beta 2 Microglobulin (B2M) Tumor Marker Test?

A Beta 2 Microglobulin (B2M) Tumor Marker Test is a blood test used to measure the level of beta 2 microglobulin (B2M) in the body. B2M is a protein produced by cells in the body and is often elevated in people with certain types of cancers.

The test is used to help diagnose certain types of cancer, to monitor cancer treatment, and to check for recurrence of cancer after treatment. It is also used to help identify other conditions, such as multiple myeloma, non-Hodgkin lymphoma, and certain types of leukemia.

Preparing for the Test

No special preparation is required for this test. You should let your doctor know about any medications or supplements you are taking, as they could affect your results.

Procedure

The B2M tumor marker test is done with a simple blood draw. A sample of your blood will be taken from a vein in your arm. The sample will then be analyzed in a laboratory.

Types of B2M Tumor Markers

There are two types of B2M tumor markers used in the diagnosis and monitoring of cancers:

• Urine B2M—This form of B2M is found in the urine and can help diagnose certain types of cancer.
• Serum B2M—This form of B2M is found in the blood and can help diagnose and monitor certain types of cancer.

Risks

There is very little risk associated with a Beta 2 Microglobulin (B2M) Tumor Marker Test. The most common risk is slight pain and bruising at the puncture site.

Why is the Test Performed?

The Beta 2 Microglobulin (B2M) Tumor Marker Test is used to help diagnose and monitor certain types of cancers. It can also be used to help detect recurrence of cancer after treatment.

When is the Test Performed?

The B2M Tumor Marker Test is typically performed when a person has signs or symptoms that may indicate cancer. It may also be used as part of routine cancer screening or to monitor cancer during and after treatment.