Relapsed Chronic Lymphocytic Leukemia
What is Relapsed Chronic Lymphocytic Leukemia (CLL)?
Relapsed chronic lymphocytic leukemia (CLL) is an aggressive form of cancer of the blood and bone marrow that is characterized by a very slow but steady increase in the number of cancerous white blood cells, called lymphocytes. CLL is the most common type of leukemia in adults, with a tendency to occur more frequently in individuals over the age of 60.
Relapsed CLL is a term used when the leukemia returns after initial treatment. Relapsed CLL is considered an aggressive form of leukemia because of its rapid progression, and patients often feel very ill shortly after diagnosis. CLL usually responds well to treatment initially, but the cancer cells can become resistant to the therapies used and then reappear.
Symptoms of Relapsed CLL
The symptoms of relapsed CLL are similar to the initial symptoms seen with this type of cancer. The main symptom of relapsed CLL is an increase in white blood cells in the blood. Other symptoms may include:
- Fatigue
- Night sweats
- Weight loss
- Enlarged lymph nodes
- Fever
- Anemia
- Infections
Causes of Relapsed CLL
The exact cause of relapsed CLL is unknown, but research suggests that certain factors increase the risk of the cancer returning. These include:
- Age – CLL is more common in older adults, and the risk of the leukemia returning increases with age.
- Genetics – CLL can be inherited through genetics, and certain genetic mutations have been linked to an increased risk of relapse.
- Environment – Exposure to toxins and certain chemicals has been linked to an increased risk of CLL relapse.
- Treatment – Certain types of chemotherapy and radiation therapy can increase the risk of relapse.
Treatment of Relapsed CLL
The goal of treatment for relapsed CLL is to reduce the patient’s symptoms and improve their quality of life. Treatment will depend on the individual’s age, medical history, and response to previous treatments, but may include:
- Chemotherapy – chemotherapy is used to kill cancer cells and can be used alone or in combination with other treatments.
- Immunotherapy – this type of therapy uses the body’s own immune system to fight cancer cells.
- Radiation Therapy – radiation therapy is used to destroy cancer cells and may be used alone or in combination with other treatments.
- Targeted Therapy – this type of therapy is used to specifically target cancer cells and is often used in combination with other treatments.
- Stem Cell Transplant – stem cell transplants are used to replace the patient’s damaged or destroyed bone marrow with healthy stem cells.
Conclusion
Relapsed CLL is an aggressive form of cancer that can be difficult to treat. It is important that individuals with CLL get regular check ups with their doctor to monitor for any changes in their health that may indicate a relapse. With proper treatment, individuals with relapsed CLL can lead a full and active life.
