Folate supplementation therapy
Folate Supplementation Therapy
Folate supplementation therapy is the use of added folate in order to increase the intake of folate in individuals with a deficiency or those who are at risk of a deficiency. Folate is an essential B-vitamin that is needed for the maintenance of normal metabolic function and for the synthesis of DNA. Folate plays a key role in many physiological functions and its deficiency may lead to impaired cell division, impaired growth, and syptoms of megaloblastic anemia.
Folate supplementation is recommended for individuals who have an inadequate dietary intake, pregnant women, individuals with certain medical conditions, those who are taking certain medications, and those who have certain genetic polymorphisms. The recommended dosages of folate supplementation may vary depending on age, sex, and medical condition.
Health Benefits of Folate Supplementation
- Folate supplementation may reduce the risk of neural tube defects in newborns.
- Folate supplementation may reduce the risk of cardiovascular disease.
- Folate supplementation may reduce the risk of stroke.
- Folate supplementation may reduce the risk of cognitive decline.
- Folate supplementation may reduce the risk of some types of cancer.
- Folate supplementation may help reduce levels of homocystein, which is implicated in heart disease.
Folate supplementation therapy is generally well tolerated and has few side effects. The most common side effects of folate supplementation in high doses includes nausea, mild diarrhea, abdominal cramps, and headache.
