Liver Transplant Rejection
What is Liver Transplant Rejection
Liver transplant rejection is a condition that occurs when the body's immune system attacks the donated liver. It can occur immediately after transplant surgery, or later on. This kind of rejection can cause serious complications and can lead to graft failure or even death.
Causes of Liver Transplant Rejection
Liver transplant rejection is caused by the body’s reaction to the donor organ. Immunological (antibody-mediated) or cell-mediated reactions can be the cause. The antibodies and cells can damage the transplanted organ (graft) and cause rejection.
Symptoms of Liver Transplant Rejection
- Abdominal pain or discomfort
- Fever
- Decreased urine output
- Weight gain or loss
- High liver enzymes
Treatment for Liver Transplant Rejection
Treatment for liver transplant rejection may involve drugs such as corticosteroids and other immunosuppressant medicines. These drugs help suppress the immune system to reduce the body's rejection of the transplanted liver. Other therapies, such as plasma exchange and plasmapheresis, may be used to reduce the body's immune response.
Outlook for Liver Transplant Rejection
The prognosis for patients with liver transplant rejection varies. It is important to identify and treat the rejection early, as it can cause serious complications, such as graft failure. If the rejection is identified and treated early, the outlook is generally good and the patient can live a normal life after the transplant.
