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| Cartilage | Bone |
| 1. Matrix is covered by a sheath of collagenous fibres called perichondrium. | Matrix is surrounded by an outer tough membrane called periosteum. |
| 2. Cartilage is ilexible. | Bone is rigid. |
| 3. Haversian system is absent. | Haversian system is present in mammalian bones. |
| 4. Matrix is made up of chondrin. | Matrix is made up of ossein. |
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