Patients who are administered OKT3 do not suffer from an acute renal allograft rejection. Why?
Patients who are administered OKT3 do not suffer from an acute renal allograft rejection. Why?
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T-cells play a major role in rejection of foreign grafts and hence they are responsible for the kidney transplant rejection.
OKT3 is a monoclonal antibody that targets CD3 surface markers (antigens) present on mature T- cells and remove them from circulation and hence prevent acute renal allograft rejection.
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