Transformation of normal cells into cancerous neoplastic cells may be induced by following physical, chemical or biological agents causing DNA damage:
● Ionising radiations like X-rays and gamma rays
● Non-ionizing radiations like UV.
● Chemical carcinogens present in tobacco smoke
● Cellular oncogenes (c-onc) or proto-oncogenes, when activated under certain conditions cause cancer. Viruses with oncogenes can transform normal cells to cancerous cells.
OR
If the person has sustained high fever (39° to 40°C), weakness, stomach pain, constipation, headache and loss of appetite, it is Typhoid.
If the person has fever, chills, cough and headache; and the lips and fingernails turn gray to bluish, it is Pneumonia.
If the person has chills and high fever recurring every three to four days then, it is Malaria.