Write the chemical equations involved in the following reactions: (i) Hoffmann-bromamide degradation reaction (ii) Carbylamine reaction
Write the chemical equations involved in the following reactions:
(i) Hoffmann-bromamide degradation reaction
(ii) Carbylamine reaction
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Hoffmann-bromamide degradation reaction : It is given by the primary amine having one carbon less.
`underset(1^(@)"amide")(R-CON)H_(2) + Br_(2) + 4KOH to underset((1^(@)"amine"))(RNH_(2)) + K_(2)Co_(3) + 2KBr + 2H_(2)O`
(ii) Carbylamine reaction : Both aliphatic and aromatic `1^(@)` amines when warmed with chlloroform and alcoholic KOH solution, produce isocyanide.
`underset((1^(@)"amine"))(R-NH_(2)) + CHCI_(3) + 3KOH(alc) overset(Delta)(to) underset(("isocyanide"))(R-NC) + 3KCI + 3H_(2)O`
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