In modern medicine, certain infectious neurological diseases were found to be transmitted by abnormally folded proteins. These proteins are called prions. The word prion comes from ‘proteinaceous infectious particle’, e.g. mad cow disease in cattle, Jacob’s disease in human. Find more information about prions.

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Prions: 

1. A prion is a misfolded form of a protein generally present in brain cells. 

2. When the prion gets into a cell containing the normal form of the protein, the prion somehow converts normal protein molecules to the misfolded prion versions. 

3. Several prions then aggregate into a complex that can convert other normal proteins to prions. 

4. Prions can be transmitted through blood, surgical instruments and contaminated food. 

5. Diseases caused by prions are Bovine Spongiform Encephalopathy in cattles, Kuru and Creutzfeldt – Jakob disease in humans.

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