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| Viruses | Viroids |
| 1. They have high molecular weight. | They have low molecular weight. |
| 2. They are larger in size. | They are smaller in size. |
| 3. They can infect plant, animals and bacteria. | They mainly infect plants. |
| 4. The genetic material can be ssRNA, ds-RNA or DNA. | The genetic material is single stranded circular RNA. |
| 5. Protein coat is present. | Protein coat is absent. |
| 6. mosaic disease is a plant disease caused by viruses. | Tomato chloric dwarf is a plant disease caused by viroids. |
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