Assertion (A): Enzymes have active sites that hold substrate molecule for a chemical reaction . Reason (R) : Drugs compete with natural substrate by a
Assertion (A): Enzymes have active sites that hold substrate molecule for a chemical reaction .
Reason (R) : Drugs compete with natural substrate by attaching covalently to active site of enzyme.
A. (A) and (R ) both are correct statement but reason does not explain (A)
B. (A) and (R ) both are correct statements and (R ) explains the (A)
C. Both (A) and (R ) are wrong statement
D. (A) is correct statement and (R ) is wrong statement
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Correct Answer - D
Drugs compete with the nuturnl substrate for their attachment on the active site of enzymes by weak bonds such as ionic bonding, H-bonding, van der Waals
interactions or dipole-dipole interactions.
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