Consider the following four statements (I-IV) regarding kidney transplant and select the two correct ones out of these.

Consider the following four statements (I-IV) regarding kidney transplant and select the two correct ones out of these. 

I. Even if a kidney transplant is proper the recipient may need to take immuno-suppresants for a long time. 

II. The cell-mediated immune response is responsible is the graft rejection. 

III. The B-lymphocytes are responsible for rejection of the graft. 

IV. The acceptance or rejection of a kidney transplant depends on specific interferons. 

The two correct statements are

(a) II and III

(b) III and IV

(c) I and III

(d) I and II