The sensation of fatigue in the muscles after prolonged strenuous physical work is caused by 

(a) a decrease in the supply of oxygen 

(b) minor wear and tear of muscle fibres 

(c) the depletion of glucose 

(d) the accumulation of lactic acid

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1 Answers

(d) Fatigue is caused by excess anaerobic metabolism, which results in production of excess lactic acid. This lactic acid causes the muscle pain.

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