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Molecular Interaction Maps, also known as MIMs, is a graphic notation to depict cellular and molecular interactions. It was created by Kurt W. Kohn in 1999. The MIM convention is capable of unambiguous representation of networks containing multi-protein complexes, protein modifications, and enzymes that are substrates of other enzymes. This graphical representation makes it possible to view all of the many interactions in which a given molecule may be involved, and it can portray competing interactions, which are common in bioregulatory networks. In order to facilitate linkage to databases, each molecular species is represented only once in a diagram. The MIM notation forms the basis of, and further development of the MIM notation is coordinated with, the Systems Biology Graphical Notation consortium, an international effort to standardize diagrams depicting biochemical and cellular processes studied in systems biology. An update to the notation was published in 2006.