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In enzymology, a RNA uridylyltransferase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are UTP and RNAn, whereas its two products are diphosphate and RNAn+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups. The systematic name of this enzyme class is UTP:RNA uridylyltransferase. Other names in common use include terminal uridylyltransferase, and TUT.

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