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In enzymology, an oligosaccharide-diphosphodolichol diphosphatase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are oligosaccharide-diphosphodolichol and H2O, whereas its two products are oligosaccharide phosphate and dolichyl phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is oligosaccharide-diphosphodolichol phosphodolichohydrolase. This enzyme is also called oligosaccharide-diphosphodolichol pyrophosphatase.

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