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In enzymology, a sepiapterin deaminase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are sepiapterin and H2O, whereas its two products are xanthopterin-B2 and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is sepiapterin aminohydrolase.

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