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In enzymology, a D-glutaminase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are D-glutamine and H2O, whereas its two products are D-glutamate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is D-glutamine amidohydrolase. This enzyme participates in d-glutamine and d-glutamate metabolism and nitrogen metabolism.

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