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In enzymology, an alpha-amino-acid esterase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are alpha-amino acid ester and H2O, whereas its two products are alpha-amino acid and alcohol.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is alpha-amino-acid-ester aminoacylhydrolase. This enzyme is also called alpha-amino acid ester hydrolase.

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