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The enzyme malyl-CoA lyase catalyzes the chemical reaction

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is -3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase. Other names in common use include malyl-coenzyme A lyase, and -3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

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