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Pipe dope is any thread lubricant, thread sealing compound, or anaerobic chemical sealant that is used to make a pipe thread joint leak proof and pressure tight. It is also referred to as "thread compound" or "pipe thread sealant." Although common pipe threads are tapered and therefore will achieve an interference fit during proper assembly, machining and finishing variances usually result in a fit that does not result in 100 percent contact between the mating components. The application of pipe dope prior to assembly will fill the minute voids between the threads, thus making the joint pressure tight. Pipe dope also acts as a lubricant and helps prevent seizing of the mating parts, which can later cause difficulty during disassembly.

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