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In enzymology, a nucleoside ribosyltransferase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are D-ribosyl-base1 and base2, whereas its two products are D-ribosyl-base2 and base1.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is nucleoside:purine D-ribosyltransferase. This enzyme is also called nucleoside N-ribosyltransferase.

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