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The cardiac transient outward potassium current is one of the ion currents across the cell membrane of heart muscle cells. It is the main contributing current during the repolarizing phase 1 of the cardiac action potential. It is a result of the movement of positively charged potassium ions from the intracellular to the extracellular space. Ito1 is complemented with Ito2 resulting from Cl ions to form the transient outward current Ito.
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