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In enzymology, a tetrahydroxynaphthalene reductase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are scytalone and NADP, whereas its 3 products are 1,3,6,8-tetrahydroxynaphthalene, NADPH, and H.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is scytalone:NADP Delta5-oxidoreductase.

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