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The Mesozoic marine revolution refers to the increase in shell-crushing and boring predation in benthic organisms throughout the Mesozoic era. The term was first coined by Geerat J. Vermeij, who based his work on that of Steven M. Stanley. While initially restricted to the Late Cretaceous , more recent studies have suggested that the beginning of this ecological arms race extends back into the Norian. It is an important transition between the Palaeozoic evolutionary fauna and the Cenozoic evolutionary fauna that occurred throughout the Mesozoic.

The Mesozoic marine revolution was not the first bout of increased predation pressure; that occurred around the end of the Ordovician.

There is some evidence of adaptation to durophagy during the Palaeozoic, particularly in crinoids.

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