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NADH dehydrogenase is an enzyme that converts nicotinamide adenine dinucleotide from its reduced form to its oxidized form. Members of the NADH dehydrogenase family and analogues are commonly systematically named using the format NADH:acceptor oxidoreductase. The chemical reaction these enzymes catalyze are generally represented with the follow equation;
NADH dehydrogenase is a flavoprotein that contains iron-sulfur centers.
NADH dehydrogenase is used in the electron transport chain for generation of ATP.
The EC term NADH dehydrogenase is defined for NADH dehydrogenases that use a quinone as the acceptor. The EC term NADH dehydrogenase is defined for those with ubiquinone as the acceptor.