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In enzymology, a carboxymethyloxysuccinate lyase is an enzyme that catalyzes the chemical reaction

Hence, this enzyme has one substrate, carboxymethyloxysuccinate, and two products, fumarate and glycolate.

This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that cleave carbon-oxygen bonds. The systematic name of this enzyme class is carboxymethyloxysuccinate glycolate-lyase. Other names in common use include carbon-oxygen lyase, and carboxymethyloxysuccinate glycolate-lyase.

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