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The tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group is a protecting group used in organic synthesis.
The BOC group can be added to the amine under aqueous conditions using di-tert-butyl dicarbonate in the presence of a base such as sodium carbonate:
Protection of the amine can also be accomplished in acetonitrile solution using 4-dimethylaminopyridine as the base.
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