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Guanosine monophosphate , also known as 5′-guanidylic acid or guanylic acid , is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside guanosine. GMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase guanine; hence it is a ribonucleoside monophosphate. Guanosine monophosphate is commercially produced by microbial fermentation.

As an acyl substituent, it takes the form of the prefix guanylyl-.

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