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The medical effects of the atomic bomb on Hiroshima upon humans can be put into the four categories below, with the effects of larger thermonuclear weapons producing blast and thermal effects so large that there would be a negligible number of survivors close enough to the center of the blast who would experience prompt/acute radiation effects, which were observed after the 16 kiloton yield Hiroshima bomb, due to its relatively low yield:
Depending on whether individuals further afield shelter in place or evacuate perpendicular to the direction of the wind, and therefore avoid contact with the fallout plume, and stay there for the days and weeks after the nuclear explosion, their exposure to fallout, and therefore their total dose, will vary. With those who do shelter in place, and or evacuate, experiencing a total dose that would be negligible in comparison to someone who just went about their life as normal.
Staying indoors until after the most hazardous fallout isotope, I-131 decays away to 0.1% of its initial quantity after ten half-lives – which is represented by 80 days in the care of I-131 cases, would make the difference between likely contracting thyroid cancer or escaping completely from this substance depending on the actions of the individual.
Some scientists estimate that if there were a nuclear war resulting in 100 Hiroshima-size nuclear explosions on cities, it could cause significant loss of life in the tens of millions from long term climatic effects alone. The climatology hypothesis is that if each city firestorms, a great deal of soot could be thrown up into the atmosphere which could blanket the earth, cutting out sunlight for years on end, causing the disruption of food chains, in what is termed a nuclear winter scenario.