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Cobalt poisoning is intoxication caused by excessive levels of cobalt in the body. Cobalt is an essential element for health in animals in minute amounts as a component of Vitamin B12. A deficiency of cobalt, which is very rare, is also potentially lethal, leading to pernicious anemia.

Exposure to cobalt metal dust is most common in the fabrication of tungsten carbide. Another source is from wear and tear of certain metal-on-metal hip prostheses.

Per the International Agency for Research on Cancer , cobalt metal with tungsten carbide is "probably carcinogenic to humans" , whereas cobalt metal without tungsten carbide is "possibly carcinogenic to humans".

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