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Dioxins and dioxin-like compounds are a group of chemical compounds that are persistent organic pollutants in the environment. They are mostly by-products of burning or various industrial processes - or, in case of dioxin-like PCBs and PBBs, unwanted minor components of intentionally produced mixtures.
Some of them are highly toxic, but the toxicity among them varies 30,000-fold. They are grouped together because their mechanism of action is the same. They activate the aryl hydrocarbon receptor , albeit with very different binding affinities, leading to high differences in toxicity and other effects. They include:
Polychlorinated dibenzo-p-dioxins
Polychlorinated dibenzofurans
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