9 views

1 Answers

A catch bond is a type of noncovalent bond whose dissociation lifetime increases with tensile force applied to the bond. Normally, bond lifetimes are expected to diminish with force. In the case of catch bonds, the lifetime of the bond actually increases up to a maximum before it decreases like in a normal bond. Catch bonds work in a way that is conceptually similar to that of a Chinese finger trap. While catch bonds are strengthened by an increase in force, the force increase is not necessary for the bond to work. Catch bonds were suspected for many years to play a role in the rolling of leukocytes, being strong enough to roll in presence of high forces caused by high shear stresses, while avoiding getting stuck in capillaries where the fluid flow, and therefore shear stress, is low. The existence of catch bonds was debated for many years until strong evidence of their existence was found in bacteria. Definite proof of their existence came shortly thereafter in leukocytes.

9 views

Related Questions

What is Ligand bond number?
1 Answers 4 Views
What is Oil catch tank?
1 Answers 4 Views
What is Bond Formation?
1 Answers 4 Views
What is Bond Tender Offer?
1 Answers 8 Views
What is Private activity bond?
1 Answers 4 Views
What is Back-bond?
1 Answers 6 Views
What is Bond equivalent yield?
1 Answers 4 Views