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In statistical theory, a U-statistic is a class of statistics that is especially important in estimation theory; the letter "U" stands for unbiased. In elementary statistics, U-statistics arise naturally in producing minimum-variance unbiased estimators.

The theory of U-statistics allows a minimum-variance unbiased estimator to be derived from each unbiased estimator of an estimable parameter for large classes of probability distributions. An estimable parameter is a measurable function of the population's cumulative probability distribution: For example, for every probability distribution, the population median is an estimable parameter. The theory of U-statistics applies to general classes of probability distributions.

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