What is Bleb (cell biology)?

In cell biology, a bleb is a bulge of the plasma membrane of a cell, human bioparticulate or abscess with an internal environment synonymous to that of a simple cell, characterized by a spherical, bulky morphology. It is characterized by the decoupling of the cytoskeleton from the plasma membrane, degrading the internal structure of the cell, allowing the flexibility required for the cell to separate into individual bulges or pockets of the intercellular matrix. Most commonly, blebs are seen in apoptosis but are also seen in other non-apoptotic functions. Blebbing, or zeiosis, is the formation of blebs.