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Duroziez's sign is a sign of aortic insufficiency. It consists of an audible diastolic murmur which can be heard over the femoral artery when it is compressed with the bell of a stethoscope.

It is named for French physician Paul Louis Duroziez who published its description in 1861, even though it was first described by Portuguese physician Pedro Francisco da Costa Alvarenga in 1855; for this reason it is alternatively known as the Alvarenga-Duroziez sign.

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