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Sapote oil, also known as sapuyul or sapayulo oil, is pressed from the seeds of the mamey sapote , a fruit tree native to South America. The oil is described as having an "almond-like odor" and a "mild, pleasant taste", and is also used as a cooking oil in some tropical countries.

The seeds themselves are reported to be toxic. The seed oil has been used in soaps and cosmetics, as a base for some aromatherapy compounds and as a sedative, skin tonic and hair revitalizer.

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