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Blood donations in India are conducted by organisations and hospitals through blood donation camps. Donors can also visit blood banks in hospitals to donate blood. Despite the shortage of donated blood, efforts by the government and advocacy groups over the years have helped bridge the gap between demand and supply. The number of voluntary blood donors increased from 54.4% in 2006–2007 to 83.1% in 2011–2012, with the number of blood units increasing from 4.4 million units in 2006–2007 to 9.3 million units in 2012–2013. In 2016, the Ministry of Health and Family Welfare reported a donation of 10.9 million units against a requirement of 12 million units. 12.7 million units were donated in 2020, lower than projected due to the COVID-19 pandemic. The regulatory framework for blood donation and blood bank management rests with the Central Drugs Standard Control Organisation, while technical bodies like the National Blood Transfusion Council and National AIDS Control Organisation formulate guidelines and recommendations for transfusion medicine and blood bank management.

Healthy individuals can donate around 350 millilitres of blood. Donors are provided with refreshments after the procedure, which usually include glucose drinks, biscuits and fruits. Some organisations offer transportation facilities, as well as certificates or badges as gratitude.

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