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The frog test is a pregnancy testing method relying on frogs to show the pregnancy status of women. Provided that immunological pregnancy tests were not yet developed before 1960s, women living a century ago relied on urine-based pregnancy tests using different animals, ranging from mice to frogs. Nowadays, the advancement in medical technology has enabled women to accurately check their pregnancy status by using 'pee-on-a-stick' pregnancy test kits at home. Before these accessible and convenient test kits were invented, scientists strived to discover a way in spotting pregnancy-related hormones by a natural, simple test, where animals were often included as clinical tools to facilitate the process. The frog test or frog pregnancy test is one of the past prevalent pregnancy scanning methods.
Throughout history, there have been different frog tests with the aim of indicating the pregnancy status of women. The most well known frog test, is the Hogben test, which is a pregnancy testing method prevalent throughout the 1940s to 1960s, by using the underlying principle of hormones and its subsequent biological response in both genders of certain frog species. The Galli-Mainini test is another frog test developed based on similar principles.
Widespread export and traffic in African clawed frogs used for these tests is believed to have been the primary cause of the intercontinental spread of chytridiomycosis.