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Menthol is an organic compound, more specifically a monoterpenoid, made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, clear or white crystalline substance, which is solid at room temperature and melts slightly above.
The main form of menthol occurring in nature is -menthol, which is assigned the configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation. Menthol also acts as a weak κ-opioid receptor agonist.
In 2017, it was the 193rd most commonly prescribed medication in the United States, with more than two million prescriptions.